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Gene: Col4a1 (collagen, type IV, alpha 1) Mus musculus
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Symbol: Col4a1
Name: collagen, type IV, alpha 1
Description: Predicted to have extracellular matrix structural constituent conferring tensile strength and platelet-derived growth factor binding activity. Involved in cellular response to amino acid stimulus; collagen-activated tyrosine kinase receptor signaling pathway; and neuromuscular junction development. Localizes to the collagen type IV trimer. Used to study COL4A1-related familial vascular leukoencephalopathy; Walker-Warburg syndrome; kidney disease; and porencephaly. Human ortholog(s) of this gene implicated in COL4A1-related familial vascular leukoencephalopathy and myocardial infarction. Is expressed in several structures, including alimentary system; brain; egg cylinder; genitourinary system; and sensory organ. Orthologous to human COL4A1 (collagen type IV alpha 1 chain).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha-1 type IV collagen; alpha1(IV) collagen; Bru; Col4a-1; collagen alpha-1(IV) chain; Del(8)44H; Del(8)Bru44H; procollagen, type IV, alpha 1; Raw; retinal anterior wiring; Svc
Orthologs:
Homo sapiens (human) : COL4A1 (collagen type IV alpha 1 chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Col4a1 (collagen type IV alpha 1 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col4a1 (collagen type IV alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL4A1 (collagen type IV alpha 1 chain)
Canis lupus familiaris (dog) : COL4A1 (collagen type IV alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col4a1 (collagen type IV alpha 1 chain)
Sus scrofa (pig) : COL4A1 (collagen type IV alpha 1 chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl811,198,423 - 11,312,826 (-)Ensembl
GRCm38811,198,423 - 11,312,889 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37811,198,423 - 11,312,826 (-)NCBIGRCm37mm9NCBIm37
MGSCv36811,198,403 - 11,312,702 (-)NCBImm8
Celera811,372,057 - 11,487,438 (-)NCBICelera
Cytogenetic Map8 A1.1NCBI
cM Map85.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Col4a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316171
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.