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Gene: H2AC18 (H2A clustered histone 18) Homo sapiens
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Symbol: H2AC18
Name: H2A clustered histone 18
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Aug 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: H2A; H2A histone family, member O; H2a-615; H2A.2; H2A/O; H2A/q; H2AFO; HIST2H2AA; HIST2H2AA3; HIST2H2AA4; histone 2, h2aa; histone 2, H2aa3; histone cluster 2 H2A family member a3; histone cluster 2, H2aa3; histone H2A type 2-A; histone H2A.2; histone H2A/o
Orthologs:
Mus musculus (house mouse) : H2ac18 (H2A clustered histone 18)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hist2h2aa3 (histone cluster 2 H2A family member A3)  Alliance
Canis lupus familiaris (dog) : LOC483168 (histone H2A type 2-A)
Sus scrofa (pig) : LOC102159655 (histone H2A type 2-A-like)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381149,842,218 - 149,842,751 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371149,813,785 - 149,814,318 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361148,080,409 - 148,080,942 (-)NCBINCBI36hg18NCBI36
Build 341146,635,700 - 146,636,234NCBI
Celera1122,548,196 - 122,548,729 (-)NCBI
Cytogenetic Map1q21.2NCBI
HuRef1121,205,342 - 121,205,875 (+)NCBIHuRef
CHM1_11151,210,344 - 151,210,877 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on H2AC18
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316194
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.