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Gene: Abca3 (ATP-binding cassette, sub-family A (ABC1), member 3) Mus musculus
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Symbol: Abca3
Name: ATP-binding cassette, sub-family A (ABC1), member 3
CRRD ID: 1316208
Description: Predicted to have ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Localizes to alveolar lamellar body membrane. Is expressed in several structures, including intestine; lung; metanephros; nervous system; and retina. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3); PARTICIPATES IN altered surfactant homeostasis pathway; surfactant homeostasis pathway; transport pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810036E22Rik; Abc; ABC-; ABC-C; Abc3; ATP-binding cassette sub-family A member 3; MGC90532
Orthologs:
Homo sapiens (human) : ABCA3 (ATP binding cassette subfamily A member 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abca3 (ATP binding cassette subfamily A member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abca3 (ATP binding cassette subfamily A member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCA3 (ATP binding cassette subfamily A member 3)
Canis lupus familiaris (dog) : ABCA3 (ATP binding cassette subfamily A member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101964223 (ATP-binding cassette sub-family A member 3)
Sus scrofa (pig) : ABCA3 (ATP binding cassette subfamily A member 3)
Chlorocebus sabaeus (African green monkey) : ABCA3 (ATP binding cassette subfamily A member 3)
Heterocephalus glaber (naked mole-rat) : Abca3 (ATP binding cassette subfamily A member 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391724,570,997 - 24,629,178 (+)NCBI
GRCm381724,351,921 - 24,410,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,351,950 - 24,410,201 (+)EnsemblGRCm38mm10GRCm38
MGSCv371724,488,991 - 24,547,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,079,646 - 24,137,801 (+)NCBImm8
Celera1724,865,306 - 24,922,824 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Abca3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316208
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.