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Gene: Abca3 (ATP-binding cassette, sub-family A (ABC1), member 3) Mus musculus
Symbol: Abca3
Name: ATP-binding cassette, sub-family A (ABC1), member 3
CRRD ID: 1316208
Description: Predicted to have ATPase-coupled transmembrane transporter activity and lipid transporter activity. Predicted to be involved in lipid transport. Localizes to alveolar lamellar body membrane. Is expressed in several structures, including intestine; lung; metanephros; nervous system; and retina. Used to study pulmonary alveolar proteinosis. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human ABCA3 (ATP binding cassette subfamily A member 3); PARTICIPATES IN altered surfactant homeostasis pathway; surfactant homeostasis pathway; transport pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810036E22Rik; Abc; ABC-; ABC-C; Abc3; ATP-binding cassette sub-family A member 3; MGC90532
Homo sapiens (human) : ABCA3 (ATP binding cassette subfamily A member 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abca3 (ATP binding cassette subfamily A member 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abca3 (ATP binding cassette subfamily A member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCA3 (ATP binding cassette subfamily A member 3)
Canis lupus familiaris (dog) : ABCA3 (ATP binding cassette subfamily A member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101964223 (ATP-binding cassette sub-family A member 3)
Sus scrofa (pig) : ABCA3 (ATP binding cassette subfamily A member 3)
Chlorocebus sabaeus (African green monkey) : ABCA3 (ATP binding cassette subfamily A member 3)
Heterocephalus glaber (naked mole-rat) : Abca3 (ATP binding cassette subfamily A member 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391724,570,997 - 24,629,178 (+)NCBI
GRCm381724,351,921 - 24,410,204 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1724,351,950 - 24,410,201 (+)EnsemblGRCm38mm10GRCm38
MGSCv371724,488,991 - 24,547,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,079,646 - 24,137,801 (+)NCBImm8
Celera1724,865,306 - 24,922,824 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Abca3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316208
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.