Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Epha2 (Eph receptor A2) Mus musculus
Symbol: Epha2
Name: Eph receptor A2
Description: Predicted to have transmembrane-ephrin receptor activity. Involved in several processes, including animal organ development; blood vessel morphogenesis; and negative regulation of vasculature development. Localizes to cell surface. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; endometrium; and limb. Used to study cataract 6 multiple types. Human ortholog(s) of this gene implicated in cataract 6 multiple types. Orthologous to human EPHA2 (EPH receptor A2); PARTICIPATES IN E-cadherin signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW545284; Eck; ephrin type-A receptor 2; epithelial cell kinase; Myk2; Sek-2; Sek2; tyrosine-protein kinase receptor ECK; tyrosine-protein kinase receptor MPK-5; tyrosine-protein kinase receptor SEK-2
Homo sapiens (human) : EPHA2 (EPH receptor A2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Epha2 (Eph receptor A2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epha2 (EPH receptor A2)
Pan paniscus (bonobo/pygmy chimpanzee) : EPHA2 (EPH receptor A2)
Canis lupus familiaris (dog) : EPHA2 (EPH receptor A2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epha2 (EPH receptor A2)
Sus scrofa (pig) : EPHA2 (EPH receptor A2)
Chlorocebus sabaeus (African green monkey) : EPHA2 (EPH receptor A2)
Heterocephalus glaber (naked mole-rat) : Epha2 (EPH receptor A2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl4141,301,240 - 141,329,384 (+)EnsemblGRCm38mm10GRCm38
GRCm384141,301,221 - 141,329,384 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374140,857,155 - 140,885,293 (+)NCBIGRCm37mm9NCBIm37
MGSCv364140,573,316 - 140,601,454 (+)NCBImm8
Celera4143,116,872 - 143,145,199 (+)NCBICelera
Cytogenetic Map4D3NCBI
cM Map473.67NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Epha2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316259
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.