Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B) Homo sapiens
Analyze
Symbol: BUB1B
Name: BUB1 mitotic checkpoint serine/threonine kinase B
Description: Predicted to have protein kinase activity. Predicted to be involved in meiotic sister chromatid cohesion, centromeric and mitotic spindle assembly checkpoint. Localizes to several cellular components, including the condensed chromosome outer kinetochore; perinuclear region of cytoplasm; and spindle. Implicated in mosaic variegated aneuploidy syndrome 1. Biomarker of gallbladder cancer and pancreatic cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Bub1A; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 homolog beta; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; SSK1
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381540,161,009 - 40,221,136 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371540,453,210 - 40,513,337 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361538,240,530 - 38,300,629 (+)NCBINCBI36hg18NCBI36
Build 341538,240,529 - 38,300,627NCBI
Celera1517,219,190 - 17,279,313 (+)NCBI
Cytogenetic Map15q15.1NCBI
HuRef1517,296,260 - 17,356,314 (+)NCBIHuRef
CHM1_11540,573,169 - 40,633,290 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BUB1B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316316
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.