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Gene: KAT2A (lysine acetyltransferase 2A) Homo sapiens
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Symbol: KAT2A
Name: lysine acetyltransferase 2A
Description: Exhibits several functions, including N-acyltransferase activity; histone deacetylase binding activity; and transcription coactivator activity. Involved in several processes, including histone deubiquitination; negative regulation of centriole replication; and protein acylation. Localizes to centrosome and histone acetyltransferase complex. Colocalizes with oxoglutarate dehydrogenase complex. Biomarker of lung non-small cell carcinoma.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5L2; general control of amino acid synthesis protein 5-like 2; General control of amino acid synthesis, yeast, homolog-like 2; hGCN5; histone acetyltransferase GCN5; histone acetyltransferase KAT2A; histone glutaryltransferase KAT2A; histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; MGC102791; PCAF-b; STAF97
Orthologs:
Mus musculus (house mouse) : Kat2a (K(lysine) acetyltransferase 2A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kat2a (lysine acetyltransferase 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kat2a (lysine acetyltransferase 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : KAT2A (lysine acetyltransferase 2A)
Canis lupus familiaris (dog) : KAT2A (lysine acetyltransferase 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kat2a (lysine acetyltransferase 2A)
Sus scrofa (pig) : KAT2A (lysine acetyltransferase 2A)
Chlorocebus sabaeus (African green monkey) : KAT2A (lysine acetyltransferase 2A)
Heterocephalus glaber (naked mole-rat) : Kat2a (lysine acetyltransferase 2A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1742,113,111 - 42,121,367 (-)EnsemblGRCh38hg38GRCh38
GRCh381742,113,111 - 42,121,367 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371740,265,129 - 40,273,382 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361737,518,655 - 37,526,908 (-)NCBINCBI36hg18NCBI36
Build 341737,518,656 - 37,526,872NCBI
Celera1736,920,167 - 36,928,419 (-)NCBI
Cytogenetic Map17q21.2NCBI
HuRef1736,030,209 - 36,038,464 (-)NCBIHuRef
CHM1_11740,500,904 - 40,509,157 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KAT2A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316319
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.