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Gene: BIRC6 (baculoviral IAP repeat containing 6) Homo sapiens
Symbol: BIRC6
Name: baculoviral IAP repeat containing 6
Description: Exhibits cysteine-type endopeptidase inhibitor activity and ubiquitin-protein transferase activity. Involved in negative regulation of extrinsic apoptotic signaling pathway and regulation of cytokinesis. Localizes to several cellular components, including the microtubule cytoskeleton; midbody; and trans-Golgi network.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APOLLON; baculoviral IAP repeat-containing 6; baculoviral IAP repeat-containing protein 6; BIR repeat-containing ubiquitin-conjugating enzyme; BRUCE; FLJ13726; FLJ13786; KIAA1289; RING-type E3 ubiquitin transferase BIRC6; ubiquitin-conjugating BIR domain enzyme apollon; ubiquitin-conjugating BIR-domain enzyme apollon
Mus musculus (house mouse) : Birc6 (baculoviral IAP repeat-containing 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Birc6 (baculoviral IAP repeat-containing 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Birc6 (baculoviral IAP repeat containing 6)
Pan paniscus (bonobo/pygmy chimpanzee) : BIRC6 (baculoviral IAP repeat containing 6)
Canis lupus familiaris (dog) : BIRC6 (baculoviral IAP repeat containing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Birc6 (baculoviral IAP repeat containing 6)
Sus scrofa (pig) : BIRC6 (baculoviral IAP repeat containing 6)
Chlorocebus sabaeus (green monkey) : BIRC6 (baculoviral IAP repeat containing 6)
Heterocephalus glaber (naked mole-rat) : Birc6 (baculoviral IAP repeat containing 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl232,357,028 - 32,618,899 (+)Ensembl
GRCh38232,356,907 - 32,618,899 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37232,581,735 - 32,843,966 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36232,435,600 - 32,697,470 (+)NCBINCBI36hg18NCBI36
Build 34232,493,964 - 32,754,622NCBI
Celera232,426,891 - 32,688,789 (+)NCBI
Cytogenetic Map2p22.3NCBI
HuRef232,320,949 - 32,583,634 (+)NCBIHuRef
CHM1_1232,512,260 - 32,774,075 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on BIRC6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316326
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.