Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tmem67 (transmembrane protein 67) Mus musculus
Analyze
Symbol: Tmem67
Name: transmembrane protein 67
CRRD ID: 1316347
Description: Predicted to have filamin binding activity; misfolded protein binding activity; and unfolded protein binding activity. Involved in several processes, including animal organ development; cilium assembly; and negative regulation of centrosome duplication. Localizes to MKS complex; cytoplasmic vesicle membrane; and endoplasmic reticulum membrane. Predicted to colocalize with axoneme. Is expressed in diencephalon; hindbrain lateral wall; metanephros; and organ of Corti. Used to study Joubert syndrome 6; Meckel syndrome; cystic kidney disease; and visceral heterotaxy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome (multiple); COACH syndrome; Joubert syndrome 6; Meckel syndrome 3; and nephronophthisis 11. Orthologous to human TMEM67 (transmembrane protein 67); INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 5330408M12Rik; B230117O07; b2b1163.1Clo; b2b1291.1Clo; meckel syndrome type 3 protein homolog; Meckelin; RP23-203A12.5
Orthologs:
Homo sapiens (human) : TMEM67 (transmembrane protein 67)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tmem67 (transmembrane protein 67)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tmem67 (transmembrane protein 67)
Pan paniscus (bonobo/pygmy chimpanzee) : TMEM67 (transmembrane protein 67)
Canis lupus familiaris (dog) : TMEM67 (transmembrane protein 67)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tmem67 (transmembrane protein 67)
Sus scrofa (pig) : TMEM67 (transmembrane protein 67)
Chlorocebus sabaeus (African green monkey) : TMEM67 (transmembrane protein 67)
Heterocephalus glaber (naked mole-rat) : Tmem67 (transmembrane protein 67)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39412,039,355 - 12,090,020 (-)NCBI
GRCm38412,039,355 - 12,090,020 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl412,039,355 - 12,090,020 (-)EnsemblGRCm38mm10GRCm38
MGSCv37411,966,502 - 12,015,104 (-)NCBIGRCm37mm9NCBIm37
MGSCv36411,966,792 - 12,015,104 (-)NCBImm8
Celera411,852,088 - 11,951,004 (-)NCBICelera
Cytogenetic Map4A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tmem67
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316347
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-27
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.