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Gene: ZEB2 (zinc finger E-box binding homeobox 2) Homo sapiens
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Symbol: ZEB2
Name: zinc finger E-box binding homeobox 2
Description: Exhibits DNA-binding transcription repressor activity, RNA polymerase II-specific and sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Localizes to the cytosol and nuclear lumen. Implicated in Hirschsprung's disease and Mowat-Wilson syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ42816; HSPC082; KIAA0569; SIP-1; SIP1; SMAD interacting protein 1; Smad-interacting protein 1; SMADIP1; ZFHX1B; zinc finger E-box-binding homeobox 2; zinc finger homeobox 1b; zinc finger homeobox protein 1b
Orthologs:
Mus musculus (house mouse) : Zeb2 (zinc finger E-box binding homeobox 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zeb2 (zinc finger E-box binding homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zeb2 (zinc finger E-box binding homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ZEB2 (zinc finger E-box binding homeobox 2)
Canis lupus familiaris (dog) : ZEB2 (zinc finger E-box binding homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zeb2 (zinc finger E-box binding homeobox 2)
Sus scrofa (pig) : ZEB2 (zinc finger E-box binding homeobox 2)
more info ...
Related Pseudogenes: ZEB2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382144,384,081 - 144,520,119 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372145,141,942 - 145,277,958 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362144,862,053 - 144,994,386 (-)NCBINCBI36hg18NCBI36
Build 342144,979,316 - 145,111,648NCBI
Celera2138,854,690 - 138,990,641 (-)NCBI
Cytogenetic Map2q22.3NCBI
HuRef2137,133,063 - 137,270,287 (-)NCBIHuRef
CHM1_12145,147,224 - 145,283,048 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

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