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Gene: ZC3H3 (zinc finger CCCH-type containing 3) Homo sapiens
Symbol: ZC3H3
Name: zinc finger CCCH-type containing 3
Description: Predicted to have DNA binding activity; R-SMAD binding activity; and metal ion binding activity. Involved in regulation of mRNA polyadenylation. Localizes to nucleus; INTERACTS WITH 5-aza-2'-deoxycytidine; 5-fluorouracil; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: KIAA0150; smad-interacting CPSF-like factor; SMICL; ZC3HDC3; zinc finger CCCH domain-containing protein 3; zinc finger CCCH type domain containing 3; zinc finger CCCH-type domain containing 3
Mus musculus (house mouse) : Zc3h3 (zinc finger CCCH type containing 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Zc3h3 (zinc finger CCCH type containing 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Zc3h3 (zinc finger CCCH-type containing 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ZC3H3 (zinc finger CCCH-type containing 3)
Canis lupus familiaris (dog) : ZC3H3 (zinc finger CCCH-type containing 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Zc3h3 (zinc finger CCCH-type containing 3)
Sus scrofa (pig) : ZC3H3 (zinc finger CCCH-type containing 3)
Chlorocebus sabaeus (African green monkey) : ZC3H3 (zinc finger CCCH-type containing 3)
Heterocephalus glaber (naked mole-rat) : Zc3h3 (zinc finger CCCH-type containing 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl8143,437,659 - 143,541,447 (-)EnsemblGRCh38hg38GRCh38
GRCh388143,437,655 - 143,549,729 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378144,519,825 - 144,624,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368144,590,968 - 144,694,763 (-)NCBINCBI36hg18NCBI36
Build 348144,590,974 - 144,694,746NCBI
Celera8140,831,713 - 140,933,556 (-)NCBI
Cytogenetic Map8q24.3NCBI
HuRef8139,772,578 - 139,874,905 (-)NCBIHuRef
CHM1_18144,560,281 - 144,663,535 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ZC3H3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316375
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.