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Gene: Rps6ka4 (ribosomal protein S6 kinase, polypeptide 4) Mus musculus
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Symbol: Rps6ka4
Name: ribosomal protein S6 kinase, polypeptide 4
Description: Predicted to have ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including histone-serine phosphorylation; interleukin-1-mediated signaling pathway; and positive regulation of histone modification. Predicted to localize to the cytosol and nucleoplasm. Is expressed in 1st branchial arch maxillary component; heart; maxillary process; and sensory organ. Orthologous to human RPS6KA4 (ribosomal protein S6 kinase A4); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110069D02Rik; 90 kDa ribosomal protein S6 kinase 4; 90kDa; AI848992; mitogen- and stress-activated protein kinase-2; mMSK2; Msk2; nuclear mitogen- and stress-activated protein kinase 2; ribosomal protein S6 kinase alpha-4; ribosomal protein S6 kinase, 90kD, polypeptide 4; RLSK; RSK-like protein kinase; S6K-alpha-4
Orthologs:
Homo sapiens (human) : RPS6KA4 (ribosomal protein S6 kinase A4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rps6ka4 (ribosomal protein S6 kinase A4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6ka4 (ribosomal protein S6 kinase A4)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KA4 (ribosomal protein S6 kinase A4)
Canis lupus familiaris (dog) : RPS6KA4 (ribosomal protein S6 kinase A4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6ka4 (ribosomal protein S6 kinase A4)
Sus scrofa (pig) : RPS6KA4 (ribosomal protein S6 kinase A4)
Chlorocebus sabaeus (green monkey) : RPS6KA4 (ribosomal protein S6 kinase A4)
Heterocephalus glaber (naked mole-rat) : Rps6ka4 (ribosomal protein S6 kinase A4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
NCBI Annotation Information: Annotation category: spans an assembly gap
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl196,829,085 - 6,840,636 (-)Ensembl
GRCm38196,829,084 - 6,842,145 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37196,903,574 - 6,915,091 (-)NCBIGRCm37mm9NCBIm37
MGSCv36196,896,128 - 6,907,645 (-)NCBImm8
Celera196,605,741 - 6,617,189 (-)NCBICelera
Cytogenetic Map19 ANCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rps6ka4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316378
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.