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Gene: SACS (sacsin molecular chaperone) Homo sapiens
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Symbol: SACS
Name: sacsin molecular chaperone
Description: Exhibits Hsp70 protein binding activity; chaperone binding activity; and proteasome binding activity. Involved in negative regulation of inclusion body assembly. Localizes to the mitochondrion and nucleus. Implicated in Charlevoix-Saguenay spastic ataxia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ARSACS; DKFZp686B15167; dnaJ homolog subfamily C member 29; DNAJC29; PPP1R138; sacsin; spastic ataxia of Charlevoix-Saguenay (sacsin); SPAX6
Orthologs:
Mus musculus (house mouse) : Sacs (sacsin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sacs (sacsin molecular chaperone)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sacs (sacsin molecular chaperone)
Pan paniscus (bonobo/pygmy chimpanzee) : SACS (sacsin molecular chaperone)
Canis lupus familiaris (dog) : SACS (sacsin molecular chaperone)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sacs (sacsin molecular chaperone)
Sus scrofa (pig) : SACS (sacsin molecular chaperone)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381323,328,827 - 23,433,728 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371323,902,962 - 24,007,867 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361322,800,966 - 22,840,626 (-)NCBINCBI36hg18NCBI36
Build 341322,800,966 - 22,840,626NCBI
Celera134,965,968 - 5,070,846 (-)NCBI
Cytogenetic Map13q12.12NCBI
HuRef134,715,591 - 4,820,305 (-)NCBIHuRef
CHM1_11323,871,558 - 23,976,445 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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