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Gene: Brd4 (bromodomain containing 4) Mus musculus
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Symbol: Brd4
Name: bromodomain containing 4
Description: Exhibits several functions, including RNA polymerase II C-terminal domain binding activity; chromatin binding activity; and protein serine/threonine kinase activity. Involved in several processes, including histone acetylation; inner cell mass cell proliferation; and protein autophosphorylation. Localizes to condensed nuclear chromosome; cyclin/CDK positive transcription elongation factor complex; and nuclear chromatin. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and retina. Human ortholog(s) of this gene implicated in colon cancer and idiopathic pulmonary fibrosis. Orthologous to human BRD4 (bromodomain containing 4).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Brd5; bromodomain-containing 5; bromodomain-containing protein 4; fsh-like protein; HUNK1; MCAP; mitotic chromosome-associated protein; WI-11513
Orthologs:
Homo sapiens (human) : BRD4 (bromodomain containing 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Brd4 (bromodomain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brd4 (bromodomain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : BRD4 (bromodomain containing 4)
Canis lupus familiaris (dog) : BRD4 (bromodomain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brd4 (bromodomain containing 4)
Sus scrofa (pig) : BRD4 (bromodomain containing 4)
Chlorocebus sabaeus (African green monkey) : BRD4 (bromodomain containing 4)
Heterocephalus glaber (naked mole-rat) : Brd4 (bromodomain containing 4)
more info ...
Related Pseudogenes: Gm11790  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1732,196,274 - 32,284,722 (-)EnsemblGRCm38mm10GRCm38
GRCm381732,196,272 - 32,284,743 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371732,333,219 - 32,421,068 (-)NCBIGRCm37mm9NCBIm37
MGSCv361731,924,979 - 32,013,849 (-)NCBImm8
Celera1733,114,772 - 33,202,572 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Brd4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316386
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.