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Gene: Brd4 (bromodomain containing 4) Mus musculus
Symbol: Brd4
Name: bromodomain containing 4
Description: Exhibits several functions, including RNA polymerase II C-terminal domain binding activity; chromatin binding activity; and protein serine/threonine kinase activity. Involved in several processes, including histone acetylation; inner cell mass cell proliferation; and protein autophosphorylation. Localizes to condensed nuclear chromosome; cyclin/CDK positive transcription elongation factor complex; and nuclear chromatin. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and retina. Human ortholog(s) of this gene implicated in colon cancer and idiopathic pulmonary fibrosis. Orthologous to human BRD4 (bromodomain containing 4).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Brd5; bromodomain-containing 5; bromodomain-containing protein 4; fsh-like protein; HUNK1; MCAP; mitotic chromosome-associated protein; WI-11513
Homo sapiens (human) : BRD4 (bromodomain containing 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Brd4 (bromodomain containing 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Brd4 (bromodomain containing 4)
Pan paniscus (bonobo/pygmy chimpanzee) : BRD4 (bromodomain containing 4)
Canis lupus familiaris (dog) : BRD4 (bromodomain containing 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Brd4 (bromodomain containing 4)
Sus scrofa (pig) : BRD4 (bromodomain containing 4)
Chlorocebus sabaeus (African green monkey) : BRD4 (bromodomain containing 4)
Heterocephalus glaber (naked mole-rat) : Brd4 (bromodomain containing 4)
more info ...
Related Pseudogenes: Gm11790  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1732,196,274 - 32,284,722 (-)EnsemblGRCm38mm10GRCm38
GRCm381732,196,272 - 32,284,743 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371732,333,219 - 32,421,068 (-)NCBIGRCm37mm9NCBIm37
MGSCv361731,924,979 - 32,013,849 (-)NCBImm8
Celera1733,114,772 - 33,202,572 (-)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1717.39NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Brd4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316386
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.