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Gene: SRXN1 (sulfiredoxin 1) Homo sapiens
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Symbol: SRXN1
Name: sulfiredoxin 1
Description: Exhibits oxidoreductase activity, acting on a sulfur group of donors. Involved in response to oxidative stress. Localizes to the cytosol; INTERACTS WITH (E)-cinnamyl alcohol; 1-chloro-2,4-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C20orf139; chromosome 20 open reading frame 139; dJ850E9.2; FLJ43353; Npn3; SRX; SRX1; sulfiredoxin 1 homolog; sulfiredoxin-1; YKL086W
Orthologs:
Mus musculus (house mouse) : Srxn1 (sulfiredoxin 1 homolog (S. cerevisiae))  MGI  Alliance
Rattus norvegicus (Norway rat) : Srxn1 (sulfiredoxin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Srxn1 (sulfiredoxin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SRXN1 (sulfiredoxin 1)
Canis lupus familiaris (dog) : SRXN1 (sulfiredoxin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Srxn1 (sulfiredoxin 1)
Sus scrofa (pig) : SRXN1 (sulfiredoxin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3820646,615 - 653,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3720627,259 - 634,014 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3620575,259 - 581,890 (-)NCBINCBI36hg18NCBI36
Build 3420575,269 - 581,890NCBI
Celera20722,084 - 728,715 (-)NCBI
Cytogenetic Map20p13NCBI
HuRef20578,569 - 585,325 (-)NCBIHuRef
CHM1_120627,286 - 634,040 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SRXN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316466
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.