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Gene: NLRP10 (NLR family pyrin domain containing 10) Homo sapiens
Symbol: NLRP10
Name: NLR family pyrin domain containing 10
Description: Exhibits ATPase activity and GTPase activity. Involved in defense response to Gram-negative bacterium; positive regulation of cytokine secretion; and positive regulation of defense response to bacterium. Localizes to the cytoplasm and extrinsic component of plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CLR11.1; NACHT, leucine rich repeat and PYD containing 10; NACHT, LRR and PYD domains-containing protein 10; NALP10; NLR family, pyrin domain containing 10; NOD8; nucleotide-binding oligomerization domain protein 8; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10; PAN5; PYNOD
Mus musculus (house mouse) : Nlrp10 (NLR family, pyrin domain containing 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nlrp10 (NLR family, pyrin domain containing 10)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NLRP10 (NLR family pyrin domain containing 10)
Canis lupus familiaris (dog) : NLRP10 (NLR family pyrin domain containing 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nlrp10 (NLR family pyrin domain containing 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl117,957,537 - 7,965,426 (-)Ensembl
GRCh38117,957,537 - 7,965,427 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37117,981,156 - 7,985,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36117,937,732 - 7,941,635 (-)NCBINCBI36hg18NCBI36
Build 34117,937,766 - 7,941,624NCBI
Celera118,096,691 - 8,100,602 (-)NCBI
Cytogenetic Map11p15.4NCBI
HuRef117,647,886 - 7,651,799 (-)NCBIHuRef
CHM1_1117,980,153 - 7,984,057 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NLRP10
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316559
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.