Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Serpinc1 (serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1) Mus musculus
Symbol: Serpinc1
Name: serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
Description: Predicted to have several functions, including heparin binding activity; identical protein binding activity; and serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity and response to nutrient. Localizes to collagen-containing extracellular matrix. Used to study antithrombin III deficiency. Human ortholog(s) of this gene implicated in antithrombin III deficiency; disseminated intravascular coagulation; intermediate coronary syndrome; thrombosis; and toxic shock syndrome. Is expressed in embryo; liver; neural tube; and notochord. Orthologous to human SERPINC1 (serpin family C member 1); PARTICIPATES IN coagulation cascade pathway; enoxaparin pharmacodynamics pathway; fondaparinux pharmacodynamics pathway; INTERACTS WITH 1,1-dichloroethene; aflatoxin B1; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI114908; anti-thrombin 3; antithrombin; antithrombin-III; At-3; At3; ATIII; serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1; serpin C1; serpin peptidase inhibitor, clade C, member 1
Homo sapiens (human) : SERPINC1 (serpin family C member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Serpinc1 (serpin family C member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Serpinc1 (serpin family C member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SERPINC1 (serpin family C member 1)
Canis lupus familiaris (dog) : SERPINC1 (serpin family C member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Serpinc1 (serpin family C member 1)
Sus scrofa (pig) : SERPINC1 (serpin family C member 1)
Chlorocebus sabaeus (African green monkey) : SERPINC1 (serpin family C member 1)
Heterocephalus glaber (naked mole-rat) : Serpinc1 (serpin family C member 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1160,978,585 - 161,005,863 (+)EnsemblGRCm38mm10GRCm38
GRCm381160,978,606 - 161,003,015 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371162,908,737 - 162,933,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv361162,824,166 - 162,839,687 (+)NCBImm8
Celera1163,418,142 - 163,442,757 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Serpinc1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316584
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.