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Gene: SEPTIN6 (septin 6) Homo sapiens
Symbol: SEPTIN6
Name: septin 6
Description: This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: KIAA0128; MGC16619; MGC20339; RP5-876A24.2; SEP2; SEPT2; SEPT6; septin 2; septin-6
Mus musculus (house mouse) : Sept6 (septin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Septin6 (septin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Septin6 (septin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SEPTIN6 (septin 6)
Canis lupus familiaris (dog) : SEPTIN6 (septin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Septin6 (septin 6)
Sus scrofa (pig) : SEPTIN6 (septin 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X119,615,724 - 119,693,370 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X118,749,687 - 118,827,333 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,633,715 - 118,711,361 (-)NCBINCBI36hg18NCBI36
Build 34X118,531,571 - 118,609,215NCBI
CeleraX119,204,389 - 119,281,983 (-)NCBI
Cytogenetic MapXq24NCBI
HuRefX108,243,227 - 108,320,808 (-)NCBIHuRef
CHM1_1X118,661,311 - 118,738,951 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SEPTIN6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316585
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-07-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.