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Gene: NEK3 (NIMA related kinase 3) Homo sapiens
Symbol: NEK3
Name: NIMA related kinase 3
Description: Predicted to have ATP binding activity; metal ion binding activity; and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation. Predicted to localize to the axon and cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: glycogen synthase A kinase; HSPK 36; HSPK36; hydroxyalkyl-protein kinase; MGC29949; never in mitosis A-related kinase 3; NIMA (never in mitosis gene a)-related kinase 3; NIMA-related kinase 3; nimA-related protein kinase 3; phosphorylase B kinase kinase; serine/threonine-protein kinase Nek3
Mus musculus (house mouse) : Nek3 (NIMA (never in mitosis gene a)-related expressed kinase 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nek3 (NIMA-related kinase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nek3 (NIMA related kinase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : NEK3 (NIMA related kinase 3)
Canis lupus familiaris (dog) : NEK3 (NIMA related kinase 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nek3 (NIMA related kinase 3)
Sus scrofa (pig) : NEK3 (NIMA related kinase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: Available sequence data supports two haplotypes in the human population that differ by a 1 nt indel (rs3837575) at the end of exon 10. Both haplotypes appear to encode functional proteins via alternative splicing of exon 11. The GRCh38 reference assembly includes the extra nt and expresses a full-length protein that includes exon 11, whereas haplotypes that lack the extra nt express a full-length protein lacking exon 11. [30 Sep 2019]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381352,132,643 - 52,159,597 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371352,706,779 - 52,733,996 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361351,604,780 - 51,631,997 (-)NCBINCBI36hg18NCBI36
Build 341351,604,779 - 51,631,511NCBI
Celera1333,755,426 - 33,782,643 (-)NCBI
Cytogenetic Map13q14.3NCBI
HuRef1333,494,915 - 33,522,031 (-)NCBIHuRef
CHM1_11352,674,859 - 52,702,079 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NEK3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316605
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.