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Gene: TRIM6 (tripartite motif containing 6) Homo sapiens
Symbol: TRIM6
Name: tripartite motif containing 6
CRRD ID: 1316640
Description: Exhibits several functions, including identical protein binding activity; protein tyrosine kinase binding activity; and ubiquitin protein ligase activity. Involved in several processes, including cellular response to interferon-beta; positive regulation of immune response; and positive regulation of protein phosphorylation. Localizes to cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: RING finger protein 89; RING-type E3 ubiquitin transferase TRIM6; RNF89; tripartite motif-containing 6; tripartite motif-containing protein 6
Mus musculus (house mouse) : Trim6 (tripartite motif-containing 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Trim6 (tripartite motif containing 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Trim6 (tripartite motif containing 6)
Pan paniscus (bonobo/pygmy chimpanzee) : TRIM6 (tripartite motif containing 6)
Canis lupus familiaris (dog) : TRIM6 (tripartite motif containing 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Trim6 (tripartite motif containing 6)
Sus scrofa (pig) : LOC100622028 (tripartite motif-containing protein 6)
Chlorocebus sabaeus (African green monkey) : TRIM6 (tripartite motif containing 6)
Heterocephalus glaber (naked mole-rat) : Trim6 (tripartite motif containing 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl115,596,109 - 5,612,958 (+)EnsemblGRCh38hg38GRCh38
GRCh38115,596,111 - 5,612,952 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37115,617,331 - 5,634,188 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,573,923 - 5,590,764 (+)NCBINCBI36hg18NCBI36
Build 34115,573,922 - 5,590,764NCBI
Celera115,735,961 - 5,753,014 (+)NCBI
Cytogenetic Map11p15.4NCBI
HuRef115,275,183 - 5,292,762 (+)NCBIHuRef
CHM1_1115,616,290 - 5,633,137 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on TRIM6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316640
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.