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Gene: Cyp39a1 (cytochrome P450, family 39, subfamily a, polypeptide 1) Mus musculus
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Symbol: Cyp39a1
Name: cytochrome P450, family 39, subfamily a, polypeptide 1
CRRD ID: 1316686
Description: Exhibits oxysterol 7-alpha-hydroxylase activity and steroid 7-alpha-hydroxylase activity. Involved in bile acid biosynthetic process and cholesterol catabolic process. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human CYP39A1 (cytochrome P450 family 39 subfamily A member 1); PARTICIPATES IN bile acid biosynthetic pathway; cerebrotendinous xanthomatosis pathway; congenital bile acid synthesis defect pathway; INTERACTS WITH (24S)-24-hydroxycholesterol; 1,2-dichloroethane; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 24-hydroxycholesterol 7-alpha-hydroxylase; cytochrome P450 39A1; cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase); mCYP39A1; oxysterol 7-alpha-hydroxylase; oxysterol 7alpha-hydroxylase
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,978,263 - 44,062,322 (+)NCBI
GRCm381743,667,372 - 43,751,431 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,667,425 - 43,751,431 (+)EnsemblGRCm38mm10GRCm38
MGSCv371743,804,374 - 43,888,380 (+)NCBIGRCm37mm9NCBIm37
MGSCv361743,130,480 - 43,214,486 (+)NCBImm8
Celera1747,090,227 - 47,177,420 (+)NCBICelera
Cytogenetic Map17B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cyp39a1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316686
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.