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Gene: SMC5 (structural maintenance of chromosomes 5) Homo sapiens
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Symbol: SMC5
Name: structural maintenance of chromosomes 5
Description: Predicted to have ATP binding activity. Involved in DNA recombination; cellular senescence; and positive regulation of maintenance of mitotic sister chromatid cohesion. Localizes to the cell junction; chromosome; and nuclear body; INTERACTS WITH aflatoxin M1; all-trans-retinoic acid; arsenous acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hSMC5; KIAA0594; SMC protein 5; SMC-5; SMC5 structural maintenance of chromosomes 5-like 1; smc5 structural maintenance of chromosomes 5-like 1 (yeast); SMC5L1; structural maintenance of chromosomes protein 5
Orthologs:
Mus musculus (house mouse) : Smc5 (structural maintenance of chromosomes 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Smc5 (structural maintenance of chromosomes 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smc5 (structural maintenance of chromosomes 5)
Pan paniscus (bonobo/pygmy chimpanzee) : SMC5 (structural maintenance of chromosomes 5)
Canis lupus familiaris (dog) : SMC5 (structural maintenance of chromosomes 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smc5 (structural maintenance of chromosomes 5)
Sus scrofa (pig) : SMC5 (structural maintenance of chromosomes 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38970,258,962 - 70,354,873 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37972,873,878 - 72,969,789 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36972,063,698 - 72,159,609 (+)NCBINCBI36hg18NCBI36
Build 34970,103,458 - 70,196,886NCBI
Celera943,464,262 - 43,560,152 (+)NCBI
Cytogenetic Map9q21.12NCBI
HuRef942,713,635 - 42,809,515 (+)NCBIHuRef
CHM1_1973,020,407 - 73,116,329 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SMC5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316718
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.