Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Kdm4c (lysine (K)-specific demethylase 4C) Mus musculus
Symbol: Kdm4c
Name: lysine (K)-specific demethylase 4C
CRRD ID: 1316777
Description: Exhibits androgen receptor binding activity; enzyme binding activity; and histone demethylase activity. Involved in several processes, including blastocyst formation; histone H3-K9 demethylation; and negative regulation of histone H3-K9 trimethylation. Localizes to pericentric heterochromatin. Is expressed in early conceptus; eye; genitourinary system; hippocampus; and rib. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to human KDM4C (lysine demethylase 4C); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410141F18Rik; [histone H3]-trimethyl-L-lysine(9) demethylase 4C; AA517467; Gasc1; gene amplified in squamous cell carcinoma 1; jmjC domain-containing histone demethylation protein 3C; Jmjd2c; jumonji domain containing 2C; jumonji domain-containing protein 2C; lysine-specific demethylase 4C
Homo sapiens (human) : KDM4C (lysine demethylase 4C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm4c (lysine demethylase 4C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm4c (lysine demethylase 4C)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM4C (lysine demethylase 4C)
Canis lupus familiaris (dog) : KDM4C (lysine demethylase 4C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm4c (lysine demethylase 4C)
Sus scrofa (pig) : KDM4C (lysine demethylase 4C)
Chlorocebus sabaeus (African green monkey) : KDM4C (lysine demethylase 4C)
Heterocephalus glaber (naked mole-rat) : Kdm4c (lysine demethylase 4C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39474,160,734 - 74,324,101 (+)NCBI
GRCm38474,242,497 - 74,405,864 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl474,242,497 - 74,405,860 (+)EnsemblGRCm38mm10GRCm38
MGSCv37473,888,401 - 74,051,768 (+)NCBIGRCm37mm9NCBIm37
MGSCv36473,723,179 - 73,877,092 (+)NCBImm8
Celera472,763,879 - 72,927,310 (+)NCBICelera
Cytogenetic Map4C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm4c
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316777
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.