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Gene: Kdm4c (lysine (K)-specific demethylase 4C) Mus musculus
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Symbol: Kdm4c
Name: lysine (K)-specific demethylase 4C
CRRD ID: 1316777
Description: Exhibits androgen receptor binding activity; enzyme binding activity; and histone demethylase activity. Involved in several processes, including blastocyst formation; histone H3-K9 demethylation; and negative regulation of histone H3-K9 trimethylation. Localizes to pericentric heterochromatin. Is expressed in early conceptus; eye; genitourinary system; hippocampus; and rib. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to human KDM4C (lysine demethylase 4C); PARTICIPATES IN histone modification pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410141F18Rik; [histone H3]-trimethyl-L-lysine(9) demethylase 4C; AA517467; Gasc1; gene amplified in squamous cell carcinoma 1; jmjC domain-containing histone demethylation protein 3C; Jmjd2c; jumonji domain containing 2C; jumonji domain-containing protein 2C; lysine-specific demethylase 4C
Orthologs:
Homo sapiens (human) : KDM4C (lysine demethylase 4C)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm4c (lysine demethylase 4C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm4c (lysine demethylase 4C)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM4C (lysine demethylase 4C)
Canis lupus familiaris (dog) : KDM4C (lysine demethylase 4C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm4c (lysine demethylase 4C)
Sus scrofa (pig) : KDM4C (lysine demethylase 4C)
Chlorocebus sabaeus (African green monkey) : KDM4C (lysine demethylase 4C)
Heterocephalus glaber (naked mole-rat) : Kdm4c (lysine demethylase 4C)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39474,160,734 - 74,324,101 (+)NCBI
GRCm38474,242,497 - 74,405,864 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl474,242,497 - 74,405,860 (+)EnsemblGRCm38mm10GRCm38
MGSCv37473,888,401 - 74,051,768 (+)NCBIGRCm37mm9NCBIm37
MGSCv36473,723,179 - 73,877,092 (+)NCBImm8
Celera472,763,879 - 72,927,310 (+)NCBICelera
Cytogenetic Map4C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kdm4c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316777
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.