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Gene: Foxe3 (forkhead box E3) Mus musculus
Symbol: Foxe3
Name: forkhead box E3
Description: Exhibits sequence-specific DNA binding activity. Involved in several processes, including camera-type eye development; negative regulation of lens fiber cell differentiation; and positive regulation of lens epithelial cell proliferation. Localizes to nucleus. Used to study congenital aphakia. Human ortholog(s) of this gene implicated in anterior segment dysgenesis; anterior segment dysgenesis 2; cataract 34 multiple types; and thoracic aortic aneurysm. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; eye; and heart. Orthologous to human FOXE3 (forkhead box E3); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dyl; dysgenetic lens; forkhead box protein E3; FREAC8; rct; Rinshoken cataract
Homo sapiens (human) : FOXE3 (forkhead box E3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Foxe3 (forkhead box E3)  Alliance
Canis lupus familiaris (dog) : FOXE3 (forkhead box E3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxe3 (forkhead box E3)
Sus scrofa (pig) : FOXE3 (forkhead box E3)
Chlorocebus sabaeus (African green monkey) : FOXE3 (forkhead box E3)
Heterocephalus glaber (naked mole-rat) : Foxe3 (forkhead box E3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4114,925,147 - 114,926,013 (-)EnsemblGRCm38mm10GRCm38
GRCm384114,924,443 - 114,926,067 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374114,597,752 - 114,598,618 (-)NCBIGRCm37mm9NCBIm37
MGSCv364114,423,079 - 114,423,945 (-)NCBImm8
Celera4113,672,921 - 113,673,787 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map452.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Foxe3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316816
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.