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Gene: FECH (ferrochelatase) Homo sapiens
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Symbol: FECH
Name: ferrochelatase
Description: Exhibits ferrochelatase activity. Involved in protoporphyrinogen IX metabolic process. Predicted to localize to the mitochondrion. Implicated in cutaneous porphyria and erythropoietic protoporphyria. Biomarker of colon adenocarcinoma and cutaneous porphyria.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EPP; EPP1; FCE; ferrochelatase, mitochondrial; heme synthase; heme synthetase; protoheme ferro-lyase; protoporphyria
Orthologs:
Mus musculus (house mouse) : Fech (ferrochelatase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fech (ferrochelatase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fech (ferrochelatase)
Pan paniscus (bonobo/pygmy chimpanzee) : FECH (ferrochelatase)
Canis lupus familiaris (dog) : FECH (ferrochelatase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fech (ferrochelatase)
Sus scrofa (pig) : FECH (ferrochelatase)
more info ...
Related Pseudogenes: FECHP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381857,544,377 - 57,586,708 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371855,212,073 - 55,253,969 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361853,366,535 - 53,404,988 (-)NCBINCBI36hg18NCBI36
Build 341853,366,534 - 53,404,988NCBI
Celera1851,928,883 - 51,970,808 (-)NCBI
Cytogenetic Map18q21.31NCBI
HuRef1851,922,248 - 51,964,183 (-)NCBIHuRef
CHM1_11855,207,292 - 55,249,187 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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References - uncurated

Genomics

Comparative Map Data
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Expression


Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on FECH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316819
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.