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Gene: FBXO4 (F-box protein 4) Homo sapiens
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Symbol: FBXO4
Name: F-box protein 4
Description: Exhibits protein homodimerization activity and ubiquitin-protein transferase activity. Involved in several processes, including cellular protein metabolic process; positive regulation of macromolecule metabolic process; and telomere maintenance. Localizes to the SCF ubiquitin ligase complex and cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp547N213; F-box only protein 4; F-box protein Fbx4; FBX4; FLJ10141
Orthologs:
Mus musculus (house mouse) : Fbxo4 (F-box protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo4 (F-box protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo4 (F-box protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO4 (F-box protein 4)
Canis lupus familiaris (dog) : FBXO4 (F-box protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo4 (F-box protein 4)
Sus scrofa (pig) : FBXO4 (F-box protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38541,918,061 - 42,040,230 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37541,925,352 - 41,941,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36541,961,113 - 41,977,429 (+)NCBINCBI36hg18NCBI36
Build 34541,961,112 - 41,970,940NCBI
Celera541,813,649 - 41,829,966 (+)NCBI
Cytogenetic Map5p13.1NCBI
HuRef541,878,053 - 41,894,370 (+)NCBIHuRef
CHM1_1541,927,213 - 41,943,529 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on FBXO4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316856
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.