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Gene: FBXO4 (F-box protein 4) Homo sapiens
Symbol: FBXO4
Name: F-box protein 4
CRRD ID: 1316856
Description: Exhibits protein homodimerization activity and ubiquitin-protein transferase activity. Involved in several processes, including cellular protein metabolic process; positive regulation of nitrogen compound metabolic process; and telomere maintenance. Localizes to SCF ubiquitin ligase complex and cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp547N213; F-box only protein 4; F-box protein Fbx4; FBX4; FLJ10141
Mus musculus (house mouse) : Fbxo4 (F-box protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fbxo4 (F-box protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fbxo4 (F-box protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : FBXO4 (F-box protein 4)
Canis lupus familiaris (dog) : FBXO4 (F-box protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fbxo4 (F-box protein 4)
Sus scrofa (pig) : FBXO4 (F-box protein 4)
Chlorocebus sabaeus (African green monkey) : FBXO4 (F-box protein 4)
Heterocephalus glaber (naked mole-rat) : Fbxo4 (F-box protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl541,925,254 - 41,941,743 (+)EnsemblGRCh38hg38GRCh38
GRCh38541,918,061 - 42,040,230 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37541,925,352 - 41,941,672 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36541,961,113 - 41,977,429 (+)NCBINCBI36hg18NCBI36
Build 34541,961,112 - 41,970,940NCBI
Celera541,813,649 - 41,829,966 (+)NCBI
Cytogenetic Map5p13.1NCBI
HuRef541,878,053 - 41,894,370 (+)NCBIHuRef
CHM1_1541,927,213 - 41,943,529 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FBXO4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316856
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.