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Gene: Ehmt1 (euchromatic histone methyltransferase 1) Mus musculus
Symbol: Ehmt1
Name: euchromatic histone methyltransferase 1
Description: Exhibits C2H2 zinc finger domain binding activity; histone methyltransferase activity (H3-K27 specific); and histone methyltransferase activity (H3-K9 specific). Involved in several processes, including macromolecule methylation; negative regulation of transcription by RNA polymerase II; and positive regulation of cold-induced thermogenesis. Localizes to the nucleus. Used to study Kleefstra syndrome. Human ortholog(s) of this gene implicated in Kleefstra syndrome. Is expressed in several structures, including alimentary system; forelimb; integumental system; nervous system; and respiratory system. Orthologous to human EHMT1 (euchromatic histone lysine methyltransferase 1); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9230102N17Rik; D330003E03; Eu-HMTase1; euchromatic histone-lysine N-methyltransferase 1; G9a-like protein 1; GLP; GLP1; histone-lysine N-methyltransferase EHMT1; KMT1D; lysine N-methyltransferase 1D; mKIAA1876
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl224,789,928 - 24,919,614 (-)Ensembl
GRCm38224,790,769 - 24,919,643 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37224,646,293 - 24,742,591 (-)NCBIGRCm37mm9NCBIm37
MGSCv36224,612,804 - 24,741,610 (-)NCBImm8
Celera224,513,064 - 24,641,648 (-)NCBICelera
Cytogenetic Map2 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ehmt1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316869
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.