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Gene: Ehmt1 (euchromatic histone methyltransferase 1) Mus musculus
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Symbol: Ehmt1
Name: euchromatic histone methyltransferase 1
Description: Exhibits C2H2 zinc finger domain binding activity; histone methyltransferase activity (H3-K27 specific); and histone methyltransferase activity (H3-K9 specific). Involved in several processes, including macromolecule methylation; negative regulation of transcription by RNA polymerase II; and positive regulation of cold-induced thermogenesis. Localizes to the nucleus. Used to study Kleefstra syndrome. Human ortholog(s) of this gene implicated in Kleefstra syndrome. Is expressed in several structures, including alimentary system; forelimb; integumental system; nervous system; and respiratory system. Orthologous to human EHMT1 (euchromatic histone lysine methyltransferase 1); PARTICIPATES IN histone modification pathway; lysine degradation pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9230102N17Rik; D330003E03; Eu-HMTase1; euchromatic histone-lysine N-methyltransferase 1; G9a-like protein 1; GLP; GLP1; histone-lysine N-methyltransferase EHMT1; KMT1D; lysine N-methyltransferase 1D; mKIAA1876
Orthologs:
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl224,789,928 - 24,919,614 (-)Ensembl
GRCm38224,790,769 - 24,919,643 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37224,646,293 - 24,742,591 (-)NCBIGRCm37mm9NCBIm37
MGSCv36224,612,804 - 24,741,610 (-)NCBImm8
Celera224,513,064 - 24,641,648 (-)NCBICelera
Cytogenetic Map2 A3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ehmt1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316869
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.