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Gene: PEX5 (peroxisomal biogenesis factor 5) Homo sapiens
Symbol: PEX5
Name: peroxisomal biogenesis factor 5
CRRD ID: 1316906
Description: Exhibits several functions, including peroxisome targeting sequence binding activity; protein C-terminus binding activity; and protein sequestering activity. Involved in negative regulation of protein-containing complex assembly; protein targeting to peroxisome; and protein tetramerization. Localizes to several cellular components, including Golgi apparatus; cytosol; and peroxisomal matrix. Implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ50634; FLJ50721; FLJ51948; PBD2A; PBD2B; peroxin-5; peroxisomal C-terminal targeting signal import receptor; peroxisomal import receptor 5; peroxisomal targeting signal 1 (SKL type) receptor; peroxisomal targeting signal 1 receptor; peroxisomal targeting signal import receptor; peroxisomal targeting signal receptor 1; peroxisome receptor 1; PTS1 receptor; PTS1-BP; PTS1R; PXR1; RCDP5
Mus musculus (house mouse) : Pex5 (peroxisomal biogenesis factor 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pex5 (peroxisomal biogenesis factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pex5 (peroxisomal biogenesis factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PEX5 (peroxisomal biogenesis factor 5)
Canis lupus familiaris (dog) : PEX5 (peroxisomal biogenesis factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pex5 (peroxisomal biogenesis factor 5)
Sus scrofa (pig) : PEX5 (peroxisomal biogenesis factor 5)
Chlorocebus sabaeus (African green monkey) : PEX5 (peroxisomal biogenesis factor 5)
Heterocephalus glaber (naked mole-rat) : Pex5 (peroxisomal biogenesis factor 5)
more info ...
Related Pseudogenes: AL390728.2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl127,188,685 - 7,218,574 (+)EnsemblGRCh38hg38GRCh38
GRCh38127,188,653 - 7,218,574 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37127,341,759 - 7,371,170 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36127,234,225 - 7,255,343 (+)NCBINCBI36hg18NCBI36
Build 34127,234,223 - 7,255,342NCBI
Celera128,917,914 - 8,946,785 (+)NCBI
Cytogenetic Map12p13.31NCBI
HuRef127,154,705 - 7,183,873 (+)NCBIHuRef
CHM1_1127,340,679 - 7,369,353 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PEX5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316906
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.