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Gene: Sp8 (trans-acting transcription factor 8) Mus musculus
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Symbol: Sp8
Name: trans-acting transcription factor 8
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in dorsal/ventral pattern formation; embryonic limb morphogenesis; and proximal/distal pattern formation. Predicted to localize to the nucleus. Is expressed in several structures, including 1st branchial arch; brain; embryo ectoderm; inner ear; and nose. Orthologous to human SP8 (Sp8 transcription factor); INTERACTS WITH 3,3',5,5'-tetrabromobisphenol A; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D930049B17Rik; mBtd; MGC105193; transcription factor Sp8
Orthologs:
Homo sapiens (human) : SP8 (Sp8 transcription factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Sp8 (Sp8 transcription factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sp8 (Sp8 transcription factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SP8 (Sp8 transcription factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sp8 (Sp8 transcription factor)
Sus scrofa (pig) : SP8 (Sp8 transcription factor)
Chlorocebus sabaeus (green monkey) : SP8 (Sp8 transcription factor)
Heterocephalus glaber (naked mole-rat) : Sp8 (Sp8 transcription factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl12118,846,329 - 118,852,576 (+)Ensembl
GRCm3812118,846,288 - 118,852,578 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3712120,084,802 - 120,091,051 (+)NCBIGRCm37mm9NCBIm37
MGSCv3612119,291,658 - 119,296,678 (+)NCBImm8
MGSCv3612113,073,063 - 113,078,083 (+)NCBImm8
Cytogenetic Map12 F2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Sp8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316920
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.