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Gene: Kdm6b (KDM1 lysine (K)-specific demethylase 6B) Mus musculus
Symbol: Kdm6b
Name: KDM1 lysine (K)-specific demethylase 6B
Description: Exhibits beta-catenin binding activity; histone demethylase activity (H3-K27 specific); and sequence-specific DNA binding activity. Involved in several processes, including cellular response to hydrogen peroxide; chromatin organization; and positive regulation of cold-induced thermogenesis. Localizes to the nucleus. Is expressed in embryo. Orthologous to human KDM6B (lysine demethylase 6B); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700064E03Rik; BC038313; jmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain-containing protein 3; KIAA0346; lysine-specific demethylase 6B; mKIAA0346; RP23-5O23.5
Homo sapiens (human) : KDM6B (lysine demethylase 6B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm6b (lysine demethylase 6B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm6b (lysine demethylase 6B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM6B (lysine demethylase 6B)
Canis lupus familiaris (dog) : KDM6B (lysine demethylase 6B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm6b (lysine demethylase 6B)
Sus scrofa (pig) : KDM6B (lysine demethylase 6B)
Chlorocebus sabaeus (green monkey) : KDM6B (lysine demethylase 6B)
Heterocephalus glaber (naked mole-rat) : Kdm6b (lysine demethylase 6B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1169,398,508 - 69,413,675 (-)Ensembl
GRCm381169,398,508 - 69,420,367 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371169,212,010 - 69,227,177 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,214,703 - 69,229,870 (-)NCBImm8
Celera1176,352,998 - 76,368,171 (-)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm6b
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316935
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.