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Gene: Kdm6b (KDM1 lysine (K)-specific demethylase 6B) Mus musculus
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Symbol: Kdm6b
Name: KDM1 lysine (K)-specific demethylase 6B
Description: Exhibits beta-catenin binding activity; histone demethylase activity (H3-K27 specific); and sequence-specific DNA binding activity. Involved in several processes, including cellular response to hydrogen peroxide; chromatin organization; and positive regulation of cold-induced thermogenesis. Localizes to the nucleus. Is expressed in embryo. Orthologous to human KDM6B (lysine demethylase 6B); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 2,3',4,4',5-Pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700064E03Rik; BC038313; jmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain-containing protein 3; KIAA0346; lysine-specific demethylase 6B; mKIAA0346; RP23-5O23.5
Orthologs:
Homo sapiens (human) : KDM6B (lysine demethylase 6B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm6b (lysine demethylase 6B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm6b (lysine demethylase 6B)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM6B (lysine demethylase 6B)
Canis lupus familiaris (dog) : KDM6B (lysine demethylase 6B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm6b (lysine demethylase 6B)
Sus scrofa (pig) : KDM6B (lysine demethylase 6B)
Chlorocebus sabaeus (green monkey) : KDM6B (lysine demethylase 6B)
Heterocephalus glaber (naked mole-rat) : Kdm6b (lysine demethylase 6B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1169,398,508 - 69,413,675 (-)Ensembl
GRCm381169,398,508 - 69,420,367 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371169,212,010 - 69,227,177 (-)NCBIGRCm37mm9NCBIm37
MGSCv361169,214,703 - 69,229,870 (-)NCBImm8
Celera1176,352,998 - 76,368,171 (-)NCBICelera
Cytogenetic Map11B3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Kdm6b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316935
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.