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Gene: Alox12e (arachidonate lipoxygenase, epidermal) Mus musculus
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Symbol: Alox12e
Name: arachidonate lipoxygenase, epidermal
Description: Exhibits arachidonate 12(S)-lipoxygenase activity and linoleate 13S-lipoxygenase activity. Involved in arachidonic acid metabolic process and lipoxygenase pathway. Predicted to localize to cytosol and plasma membrane. Is expressed in alimentary system; hemolymphoid system; integumental system; and respiratory system; PARTICIPATES IN lipoxygenase mediated pathway of arachidonic acid metabolism; arachidonic acid metabolic pathway; INTERACTS WITH (S)-nicotine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 12-LOX; 12-LOX-e; 8-L; 8-LOX; Al; Alox1; Alox12-ps1; Alox12-ps2; Aloxe; arachidonate (12S)-lipoxygenase, epidermal-type; arachidonate 12-lipoxygenase, epidermal; arachidonate 12-lipoxygenase, epidermal-type; AW259591; e(12S)-LOX; e-LO; e-LOX1; linoleate (13S)-lipoxygenase; polyunsaturated fatty acid (12S)/(13S)-lipoxygenase, epidermal-type
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl1170,315,610 - 70,322,628 (-)EnsemblGRCm38mm10GRCm38
GRCm381170,315,610 - 70,322,720 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371170,129,115 - 70,136,020 (-)NCBIGRCm37mm9NCBIm37
MGSCv361170,131,808 - 70,138,713 (-)NCBImm8
Celera1177,860,181 - 77,867,092 (-)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Alox12e
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316950
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.