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Gene: Wnt8b (wingless-type MMTV integration site family, member 8B) Mus musculus
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Symbol: Wnt8b
Name: wingless-type MMTV integration site family, member 8B
Description: Predicted to have cytokine activity and frizzled binding activity. Involved in negative regulation of gene expression and positive regulation of gene expression. Predicted to localize to extracellular space. Is expressed in several structures, including cochlea; eye; future brain; head mesenchyme; and nervous system. Human ortholog(s) of this gene implicated in Hirschsprung's disease. Orthologous to human WNT8B (Wnt family member 8B); PARTICIPATES IN Wnt signaling, canonical pathway; basal cell carcinoma pathway; Hedgehog signaling pathway; INTERACTS WITH 1,2-dichloroethane; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: protein Wnt-8b; wingless related MMTV integration site 8b
Orthologs:
Homo sapiens (human) : WNT8B (Wnt family member 8B)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Wnt8b (Wnt family member 8B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Wnt8b (Wnt family member 8B)
Pan paniscus (bonobo/pygmy chimpanzee) : WNT8B (Wnt family member 8B)
Canis lupus familiaris (dog) : WNT8B (Wnt family member 8B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Wnt8b (Wnt family member 8B)
Sus scrofa (pig) : WNT8B (Wnt family member 8B)
Chlorocebus sabaeus (African green monkey) : WNT8B (Wnt family member 8B)
Heterocephalus glaber (naked mole-rat) : Wnt8b (Wnt family member 8B)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1944,493,472 - 44,514,273 (+)EnsemblGRCm38mm10GRCm38
GRCm381944,493,472 - 44,514,273 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371944,567,962 - 44,588,763 (+)NCBIGRCm37mm9NCBIm37
MGSCv361944,546,784 - 44,565,828 (+)NCBImm8
Celera1945,276,759 - 45,282,000 (+)NCBICelera
Cytogenetic Map19C3NCBI
cM Map1937.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Wnt8b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316954
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.