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Gene: LPIN1 (lipin 1) Homo sapiens
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Symbol: LPIN1
Name: lipin 1
Description: Predicted to have phosphatidate phosphatase activity and transcription coactivator activity. Predicted to be involved in several processes, including cellular response to insulin stimulus; positive regulation of cold-induced thermogenesis; and triglyceride metabolic process. Predicted to localize to the mitochondrial outer membrane and nuclear membrane. Biomarker of morbid obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp781P1796; KIAA0188; lipin-1; PAP1; phosphatidate phosphatase LPIN1
Orthologs:
Mus musculus (house mouse) : Lpin1 (lipin 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Lpin1 (lipin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lpin1 (lipin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LPIN1 (lipin 1)
Canis lupus familiaris (dog) : LPIN1 (lipin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lpin1 (lipin 1)
Sus scrofa (pig) : LPIN1 (lipin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38211,677,544 - 11,827,409 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37211,817,705 - 11,967,535 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36211,804,191 - 11,884,986 (+)NCBINCBI36hg18NCBI36
Build 34211,837,337 - 11,918,129NCBI
Celera211,803,878 - 11,884,673 (+)NCBI
Cytogenetic Map2p25.1NCBI
HuRef211,669,235 - 11,818,856 (+)NCBIHuRef
CHM1_1211,747,316 - 11,897,077 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on LPIN1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1316957
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.