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Gene: Cavin1 (caveolae associated 1) Mus musculus
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Symbol: Cavin1
Name: caveolae associated 1
Description: Exhibits rRNA primary transcript binding activity. Involved in positive regulation of cell motility; protein secretion; and transcription, DNA-templated. Localizes to the caveola; endoplasmic reticulum; and nucleus. Used to study congenital generalized lipodystrophy type 4 and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 4. Is expressed in several structures, including genitourinary system and sensory organ. Orthologous to human CAVIN1 (caveolae associated protein 1); PARTICIPATES IN RNA polymerase I transcription pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310075E07Rik; AW546441; Cav-p60; caveolae-associated protein 1; Cavin; cavin-1; MGC118550; polymerase I and transcript release factor; ptrf
Orthologs:
Homo sapiens (human) : CAVIN1 (caveolae associated protein 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cavin1 (caveolae associated protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cavin1 (caveolae associated protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CAVIN1 (caveolae associated protein 1)
Canis lupus familiaris (dog) : CAVIN1 (caveolae associated protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cavin1 (caveolae associated protein 1)
Sus scrofa (pig) : CAVIN1 (caveolae associated protein 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl11100,956,733 - 100,970,887 (-)Ensembl
GRCm3811100,956,736 - 100,970,617 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3711100,818,050 - 100,831,931 (-)NCBIGRCm37mm9NCBIm37
MGSCv3611100,772,826 - 100,786,707 (-)NCBImm8
Celera11112,252,831 - 112,266,712 (-)NCBICelera
Cytogenetic Map11 DNCBI
cM Map1163.95NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Cavin1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317018
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.