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Gene: RIOX1 (ribosomal oxygenase 1) Homo sapiens
Symbol: RIOX1
Name: ribosomal oxygenase 1
CRRD ID: 1317046
Description: Predicted to have histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K4 specific); and iron ion binding activity. Predicted to be involved in histone lysine demethylation; negative regulation of osteoblast differentiation; and negative regulation of transcription, DNA-templated. Localizes to nucleolus; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; atrazine; bisphenol F.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 60S ribosomal protein L8 histidine hydroxylase; bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; C14orf169; chromosome 14 open reading frame 169; FLJ21802; histone lysine demethylase NO66; hsNO66; JMJD9; lysine-specific demethylase NO66; MAPJD; MYC-associated protein with JmjC domain; NO66; nucleolar protein 66; ribosomal oxygenase NO66; ROX; up-regulated in lung cancer 2; URLC2
Mus musculus (house mouse) : Riox1 (ribosomal oxygenase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Riox1 (ribosomal oxygenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Riox1 (ribosomal oxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RIOX1 (ribosomal oxygenase 1)
Canis lupus familiaris (dog) : RIOX1 (ribosomal oxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Riox1 (ribosomal oxygenase 1)
Sus scrofa (pig) : RIOX1 (ribosomal oxygenase 1)
Chlorocebus sabaeus (African green monkey) : RIOX1 (ribosomal oxygenase 1)
Heterocephalus glaber (naked mole-rat) : Riox1 (ribosomal oxygenase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1473,490,933 - 73,493,394 (+)EnsemblGRCh38hg38GRCh38
GRCh381473,490,933 - 73,493,394 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371473,957,644 - 73,960,105 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361473,027,397 - 73,029,858 (+)NCBINCBI36hg18NCBI36
Build 341473,027,421 - 73,029,850NCBI
Celera1454,021,934 - 54,024,395 (+)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1454,124,500 - 54,126,962 (+)NCBIHuRef
CHM1_11473,897,057 - 73,899,526 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RIOX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317046
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.