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Gene: Riox1 (ribosomal oxygenase 1) Mus musculus
Symbol: Riox1
Name: ribosomal oxygenase 1
CRRD ID: 1317047
Description: Exhibits histone demethylase activity (H3-K36 specific); histone demethylase activity (H3-K4 specific); and iron ion binding activity. Involved in histone lysine demethylation; negative regulation of osteoblast differentiation; and negative regulation of transcription, DNA-templated. Localizes to nucleolus. Is expressed in skeleton and tibia cartilage condensation. Orthologous to human RIOX1 (ribosomal oxygenase 1); INTERACTS WITH 4-hydroxyphenyl retinamide; genistein; pregnenolone 16alpha-carbonitrile.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410016O06Rik; bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; histone lysine demethylase NO66; lysine-specific demethylase NO66; MAPJD; myc associated protein with JmjC domain; myc-associated protein with JmjC domain; NO; NO66; nucleolar protein 66; RIKEN cDNA 2410016O06 gene
Homo sapiens (human) : RIOX1 (ribosomal oxygenase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Riox1 (ribosomal oxygenase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Riox1 (ribosomal oxygenase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RIOX1 (ribosomal oxygenase 1)
Canis lupus familiaris (dog) : RIOX1 (ribosomal oxygenase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Riox1 (ribosomal oxygenase 1)
Sus scrofa (pig) : RIOX1 (ribosomal oxygenase 1)
Chlorocebus sabaeus (African green monkey) : RIOX1 (ribosomal oxygenase 1)
Heterocephalus glaber (naked mole-rat) : Riox1 (ribosomal oxygenase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm391283,997,382 - 83,999,727 (+)NCBI
GRCm381283,950,608 - 83,952,953 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1283,950,608 - 83,952,951 (+)EnsemblGRCm38mm10GRCm38
MGSCv371285,291,558 - 85,293,903 (+)NCBIGRCm37mm9NCBIm37
MGSCv361284,840,418 - 84,842,694 (+)NCBImm8
Celera1285,397,188 - 85,399,533 (+)NCBICelera
Cytogenetic Map12D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Riox1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317047
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.