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Gene: CD3G (CD3g molecule) Homo sapiens
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Symbol: CD3G
Name: CD3g molecule
Description: The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD3-GAMMA; CD3g antigen, gamma polypeptide (TiT3 complex); CD3g molecule, epsilon (CD3-TCR complex); CD3g molecule, gamma (CD3-TCR complex); FLJ17620; FLJ17664; FLJ79544; FLJ94613; IMD17; MGC138597; T-cell antigen receptor complex, gamma subunit of T3; T-cell receptor T3 gamma chain; T-cell surface glycoprotein CD3 gamma chain; T3G
Orthologs:
Mus musculus (house mouse) : Cd3g (CD3 antigen, gamma polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cd3g (CD3g molecule)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd3g (CD3g molecule)
Pan paniscus (bonobo/pygmy chimpanzee) : CD3G (CD3g molecule)
Canis lupus familiaris (dog) : CD3G (CD3g molecule)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd3g (CD3g molecule)
Sus scrofa (pig) : CD3G (CD3g molecule)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811118,344,344 - 118,353,782 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711118,215,032 - 118,224,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611117,720,311 - 117,729,261 (+)NCBINCBI36hg18NCBI36
Build 3411117,720,310 - 117,729,261NCBI
Celera11115,372,928 - 115,382,366 (+)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11114,148,956 - 114,158,393 (+)NCBIHuRef
CHM1_111118,101,492 - 118,110,943 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CD3G
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317072
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.