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Gene: Irf7 (interferon regulatory factor 7) Mus musculus
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Symbol: Irf7
Name: interferon regulatory factor 7
CRRD ID: 1317252
Description: Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including defense response to other organism; regulation of signal transduction; and type I interferon production. Predicted to localize to cytosol and nucleoplasm. Is expressed in apical ectodermal ridge; embryo; liver; and ureter. Human ortholog(s) of this gene implicated in immunodeficiency 39. Orthologous to human IRF7 (interferon regulatory factor 7); PARTICIPATES IN hepatitis C pathway; influenza A pathway; measles pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IRF-7
Orthologs:
Homo sapiens (human) : IRF7 (interferon regulatory factor 7)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Irf7 (interferon regulatory factor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Irf7 (interferon regulatory factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Irf7 (interferon regulatory factor 7)
Sus scrofa (pig) : IRF7 (interferon regulatory factor 7)
Chlorocebus sabaeus (African green monkey) : IRF7 (interferon regulatory factor 7)
Heterocephalus glaber (naked mole-rat) : Irf7 (interferon regulatory factor 7)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,843,096 - 140,846,412 (-)NCBI
GRCm387141,263,183 - 141,266,499 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,262,706 - 141,266,481 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,449,088 - 148,452,300 (-)NCBIGRCm37mm9NCBIm37
MGSCv367141,114,509 - 141,117,721 (-)NCBImm8
Celera7141,056,921 - 141,060,133 (-)NCBICelera
Cytogenetic Map7F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Irf7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317252
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-11-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.