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Gene: Pias1 (protein inhibitor of activated STAT 1) Mus musculus
Symbol: Pias1
Name: protein inhibitor of activated STAT 1
Description: Exhibits transcription factor binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including fat cell differentiation; positive regulation of proteasomal ubiquitin-dependent protein catabolic process; and protein sumoylation. Localizes to the nucleus. Colocalizes with the PML body. Is expressed in several structures, including branchial arch; genitourinary system; sensory organ; tooth; and trunk mesenchyme. Orthologous to human PIAS1 (protein inhibitor of activated STAT 1); PARTICIPATES IN aldosterone signaling pathway; ataxia telangiectasia-mutated (ATM) signaling pathway; Hedgehog signaling pathway; INTERACTS WITH 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254.
Type: protein-coding
Also known as: 2900068C24Rik; Ddxbp1; DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1; DEAD/H box-binding protein 1; E3 SUMO-protein ligase PIAS1; GBP; protein inhibitor of activated STAT protein 1; RING-type E3 ubiquitin transferase PIAS1
Homo sapiens (human) : PIAS1 (protein inhibitor of activated STAT 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pias1 (protein inhibitor of activated STAT, 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias1 (protein inhibitor of activated STAT 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS1 (protein inhibitor of activated STAT 1)
Canis lupus familiaris (dog) : PIAS1 (protein inhibitor of activated STAT 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias1 (protein inhibitor of activated STAT 1)
Sus scrofa (pig) : PIAS1 (protein inhibitor of activated STAT 1)
Chlorocebus sabaeus (African green monkey) : PIAS1 (protein inhibitor of activated STAT 1)
Heterocephalus glaber (naked mole-rat) : Pias1 (protein inhibitor of activated STAT 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl962,878,368 - 62,987,924 (-)Ensembl
GRCm38962,878,366 - 62,980,879 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37962,727,884 - 62,828,686 (-)NCBIGRCm37mm9NCBIm37
MGSCv36962,678,083 - 62,778,885 (-)NCBImm8
Celera960,099,154 - 60,199,601 (-)NCBICelera
Cytogenetic Map9 BNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pias1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317274
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.