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Gene: IL36B (interleukin 36 beta) Homo sapiens
Symbol: IL36B
Name: interleukin 36 beta
Description: Predicted to have cytokine activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; positive regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of T cell differentiation. Predicted to localize to extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: family of interleukin 1-eta; FIL1; FIL1 eta; FIL1-(ETA); FIL1H; FILI-(ETA); IL-1 eta; IL-1F8; IL-1F8 (FIL1-eta); IL-1H2; IL1-ETA; IL1F8; IL1F8 (Canonical product IL-1F8a); IL1H2; interleukin 1 family, member 8 (eta); interleukin 1, eta; interleukin 36, beta; interleukin-1 eta; interleukin-1 family member 8; interleukin-1 homolog 2; Interleukin-1 Superfamily e; interleukin-36 beta; MGC126880; MGC126882
Mus musculus (house mouse) : Il1f8 (interleukin 1 family, member 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il36b (interleukin 36, beta)  Alliance
Canis lupus familiaris (dog) : IL36B (interleukin 36 beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il36b (interleukin 36 beta)
Heterocephalus glaber (naked mole-rat) : Il36b (interleukin 36 beta)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2113,022,089 - 113,052,867 (-)EnsemblGRCh38hg38GRCh38
GRCh382113,022,089 - 113,052,867 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,779,668 - 113,810,444 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,496,139 - 113,526,911 (-)NCBINCBI36hg18NCBI36
Build 342113,501,366 - 113,526,671NCBI
Celera2107,164,821 - 107,195,607 (-)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2106,234,584 - 106,265,349 (-)NCBIHuRef
CHM1_12113,783,819 - 113,814,595 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on IL36B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317278
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.