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Gene: ANK2 (ankyrin 2) Homo sapiens
Symbol: ANK2
Name: ankyrin 2
CRRD ID: 1317291
Description: Exhibits several functions, including ion channel binding activity; phosphorylation-dependent protein binding activity; and spectrin binding activity. Involved in several processes, including regulation of heart contraction; regulation of ventricular cardiac muscle cell membrane repolarization; and ventricular cardiac muscle cell action potential. Localizes to basolateral plasma membrane. Implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANK-2; ankyrin 2, neuronal; ankyrin B; ankyrin, brain; ankyrin, nonerythroid; ankyrin-2; ankyrin-2, nonerythrocytic; brain ankyrin; brank-2; CFAP87; DKFZp686M09125; DKFZp686P0948; FAP87; FLJ11832; FLJ38277; FLJ46169; LQT4; non-erythroid ankyrin
Mus musculus (house mouse) : Ank2 (ankyrin 2, brain)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ank2 (ankyrin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ank2 (ankyrin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ANK2 (ankyrin 2)
Canis lupus familiaris (dog) : ANK2 (ankyrin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ank2 (ankyrin 2)
Sus scrofa (pig) : ANK2 (ankyrin 2)
Chlorocebus sabaeus (African green monkey) : ANK2 (ankyrin 2)
Heterocephalus glaber (naked mole-rat) : Ank2 (ankyrin 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl4112,818,032 - 113,384,221 (+)EnsemblGRCh38hg38GRCh38
GRCh384112,705,622 - 113,383,736 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374113,739,239 - 114,304,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364114,190,319 - 114,524,337 (+)NCBINCBI36hg18NCBI36
Celera4111,031,065 - 111,596,545 (+)NCBI
Cytogenetic Map4q25-q26NCBI
HuRef4109,467,190 - 110,033,212 (+)NCBIHuRef
CHM1_14113,715,710 - 114,281,305 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences