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Gene: STXBP4 (syntaxin binding protein 4) Homo sapiens
Symbol: STXBP4
Name: syntaxin binding protein 4
Description: Exhibits syntaxin binding activity. Involved in several processes, including positive regulation of cell cycle G1/S phase transition; positive regulation of keratinocyte proliferation; and protein stabilization. Localizes to the extracellular exosome; PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 4,4'-sulfonyldiphenol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ16496; MGC149829; MGC50337; STX4-interacting protein; Synip; syntaxin 4 interacting protein; syntaxin 4-interacting protein; syntaxin-binding protein 4
Mus musculus (house mouse) : Stxbp4 (syntaxin binding protein 4)  MGI  Alliance
Rattus norvegicus (Norway rat) : Stxbp4 (syntaxin binding protein 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Stxbp4 (syntaxin binding protein 4)
Pan paniscus (bonobo/pygmy chimpanzee) : STXBP4 (syntaxin binding protein 4)
Canis lupus familiaris (dog) : STXBP4 (syntaxin binding protein 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Stxbp4 (syntaxin binding protein 4)
Sus scrofa (pig) : STXBP4 (syntaxin binding protein 4)
Chlorocebus sabaeus (green monkey) : STXBP4 (syntaxin binding protein 4)
Heterocephalus glaber (naked mole-rat) : Stxbp4 (syntaxin binding protein 4)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1754,968,727 - 55,173,632 (+)Ensembl
GRCh381754,968,728 - 55,173,632 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371753,046,119 - 53,241,646 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361750,401,125 - 50,596,448 (+)NCBINCBI36hg18NCBI36
Build 341750,401,124 - 50,596,151NCBI
Celera1749,508,379 - 49,703,707 (+)NCBI
Cytogenetic Map17q22NCBI
HuRef1748,405,512 - 48,600,855 (+)NCBIHuRef
CHM1_11753,111,024 - 53,306,373 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on STXBP4
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317366
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.