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Gene: Def6 (differentially expressed in FDCP 6) Mus musculus
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Symbol: Def6
Name: differentially expressed in FDCP 6
CRRD ID: 1317435
Description: Localizes to cell-cell junction. Is expressed in several structures, including heart; hemolymphoid system; lung; metanephros; and musculature. Used to study systemic lupus erythematosus. Orthologous to human DEF6 (DEF6 guanine nucleotide exchange factor); INTERACTS WITH 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2410003F05Rik; 6430538D02Rik; AV094905; DEF-6; I; Ibp; IRF-4-binding protein; IRF4-binding protein; S; Slat; Slat2; Slat6; SWAP-70-like adapter of T-cells
Orthologs:
Homo sapiens (human) : DEF6 (DEF6 guanine nucleotide exchange factor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Def6 (DEF6 guanine nucleotide exchange factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Def6 (DEF6 guanine nucleotide exchange factor)
Pan paniscus (bonobo/pygmy chimpanzee) : DEF6 (DEF6 guanine nucleotide exchange factor)
Canis lupus familiaris (dog) : DEF6 (DEF6 guanine nucleotide exchange factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Def6 (DEF6 guanine nucleotide exchange factor)
Sus scrofa (pig) : DEF6 (DEF6 guanine nucleotide exchange factor)
Chlorocebus sabaeus (African green monkey) : DEF6 (DEF6 guanine nucleotide exchange factor)
Heterocephalus glaber (naked mole-rat) : Def6 (DEF6 guanine nucleotide exchange factor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391728,426,752 - 28,447,582 (+)NCBI
GRCm381728,207,456 - 28,228,608 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1728,207,778 - 28,228,608 (+)EnsemblGRCm38mm10GRCm38
MGSCv371728,344,723 - 28,365,553 (+)NCBIGRCm37mm9NCBIm37
MGSCv361727,935,419 - 27,956,188 (+)NCBImm8
Celera1728,761,659 - 28,782,259 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Def6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317435
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.