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Gene: NUF2 (NUF2 component of NDC80 kinetochore complex) Homo sapiens
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Symbol: NUF2
Name: NUF2 component of NDC80 kinetochore complex
Description: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 106; CDCA1; cell division cycle associated 1; cell division cycle-associated protein 1; CT106; hNuf2; hNuf2R; hsNuf2; kinetochore protein Nuf2; NDC80 kinetochore complex component NUF2; NUF2, NDC80 kinetochore complex component; NUF2, NDC80 kinetochore complex component, homolog; NUF2R
Orthologs:
Mus musculus (house mouse) : Nuf2 (NUF2, NDC80 kinetochore complex component)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nuf2 (NUF2 component of NDC80 kinetochore complex)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nuf2 (NUF2 component of NDC80 kinetochore complex)
Pan paniscus (bonobo/pygmy chimpanzee) : NUF2 (NUF2 component of NDC80 kinetochore complex)
Canis lupus familiaris (dog) : NUF2 (NUF2 component of NDC80 kinetochore complex)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nuf2 (NUF2 component of NDC80 kinetochore complex)
Sus scrofa (pig) : NUF2 (NUF2 component of NDC80 kinetochore complex)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381163,321,933 - 163,355,764 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371163,291,723 - 163,325,553 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,558,347 - 161,592,177 (+)NCBINCBI36hg18NCBI36
Build 341160,023,382 - 160,057,205NCBI
Celera1136,396,004 - 136,429,820 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1134,537,062 - 134,570,886 (+)NCBIHuRef
CHM1_11164,714,625 - 164,748,448 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NUF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317446
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.