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Gene: NUF2 (NUF2 component of NDC80 kinetochore complex) Homo sapiens
Symbol: NUF2
Name: NUF2 component of NDC80 kinetochore complex
Description: This gene encodes a protein that is highly similar to yeast Nuf2, a component of a conserved protein complex associated with the centromere. Yeast Nuf2 disappears from the centromere during meiotic prophase when centromeres lose their connection to the spindle pole body, and plays a regulatory role in chromosome segregation. The encoded protein is found to be associated with centromeres of mitotic HeLa cells, which suggests that this protein is a functional homolog of yeast Nuf2. Alternatively spliced transcript variants that encode the same protein have been described. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cancer/testis antigen 106; CDCA1; cell division cycle associated 1; cell division cycle-associated protein 1; CT106; hNuf2; hNuf2R; hsNuf2; kinetochore protein Nuf2; NDC80 kinetochore complex component NUF2; NUF2, NDC80 kinetochore complex component; NUF2, NDC80 kinetochore complex component, homolog; NUF2R
Mus musculus (house mouse) : Nuf2 (NUF2, NDC80 kinetochore complex component)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nuf2 (NUF2 component of NDC80 kinetochore complex)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nuf2 (NUF2 component of NDC80 kinetochore complex)
Pan paniscus (bonobo/pygmy chimpanzee) : NUF2 (NUF2 component of NDC80 kinetochore complex)
Canis lupus familiaris (dog) : NUF2 (NUF2 component of NDC80 kinetochore complex)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nuf2 (NUF2 component of NDC80 kinetochore complex)
Sus scrofa (pig) : NUF2 (NUF2 component of NDC80 kinetochore complex)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381163,321,933 - 163,355,764 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371163,291,723 - 163,325,553 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361161,558,347 - 161,592,177 (+)NCBINCBI36hg18NCBI36
Build 341160,023,382 - 160,057,205NCBI
Celera1136,396,004 - 136,429,820 (+)NCBI
Cytogenetic Map1q23.3NCBI
HuRef1134,537,062 - 134,570,886 (+)NCBIHuRef
CHM1_11164,714,625 - 164,748,448 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NUF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317446
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.