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Gene: NSD2 (nuclear receptor binding SET domain protein 2) Homo sapiens
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Symbol: NSD2
Name: nuclear receptor binding SET domain protein 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and histone methyltransferase activity (H3-K36 specific). Predicted to be involved in regulation of transcription, DNA-templated. Localizes to the nucleoplasm. Implicated in Wolf-Hirschhorn syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ23286; histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; KIAA1090; KMT3F; KMT3G; MGC176638; MMSET; multiple myeloma SET domain containing protein type III; multiple myeloma SET domain-containing protein; nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; protein trithorax-5; REIIBP; trithorax/ash1-related protein 5; TRX5; WHS; WHSC1; Wolf-Hirschhorn syndrome candidate 1; wolf-Hirschhorn syndrome candidate 1 protein
Orthologs:
Mus musculus (house mouse) : Nsd2 (nuclear receptor binding SET domain protein 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nsd2 (nuclear receptor binding SET domain protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nsd2 (nuclear receptor binding SET domain protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : NSD2 (nuclear receptor binding SET domain protein 2)
Canis lupus familiaris (dog) : NSD2 (nuclear receptor binding SET domain protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nsd2 (nuclear receptor binding SET domain protein 2)
Sus scrofa (pig) : NSD2 (nuclear receptor binding SET domain protein 2)
more info ...
Related Pseudogenes: WHSC1L2P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3841,871,393 - 1,982,207 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3741,873,123 - 1,983,934 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3641,842,921 - 1,953,728 (+)NCBINCBI36hg18NCBI36
Build 3441,908,238 - 1,948,753NCBI
Celera41,806,735 - 1,896,162 (+)NCBI
Cytogenetic Map4p16.3NCBI
HuRef41,835,879 - 1,925,293 (+)NCBIHuRef
CHM1_141,871,595 - 1,982,597 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on NSD2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317450
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.