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Gene: SH2D4A (SH2 domain containing 4A) Homo sapiens
Symbol: SH2D4A
Name: SH2 domain containing 4A
Description: Exhibits phosphatase binding activity. Involved in negative regulation of phosphatase activity. Localizes to cytosol; INTERACTS WITH (-)-epigallocatechin 3-gallate; 2,3,7,8-tetrachlorodibenzodioxine; 2-hydroxypropanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: FLJ20967; PPP1R38; protein phosphatase 1 regulatory subunit 38; protein phosphatase 1, regulatory subunit 38; protein SH(2)A; SH2 domain-containing protein 4A; SH2A
Mus musculus (house mouse) : Sh2d4a (SH2 domain containing 4A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sh2d4a (SH2 domain containing 4A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sh2d4a (SH2 domain containing 4A)
Pan paniscus (bonobo/pygmy chimpanzee) : SH2D4A (SH2 domain containing 4A)
Canis lupus familiaris (dog) : SH2D4A (SH2 domain containing 4A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sh2d4a (SH2 domain containing 4A)
Sus scrofa (pig) : LOC100518097 (SH2 domain-containing protein 4A)
Chlorocebus sabaeus (African green monkey) : SH2D4A (SH2 domain containing 4A)
Heterocephalus glaber (naked mole-rat) : Sh2d4a (SH2 domain containing 4A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl819,313,693 - 19,396,218 (+)EnsemblGRCh38hg38GRCh38
GRCh38819,313,570 - 19,396,218 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37819,171,081 - 19,253,729 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36819,215,483 - 19,297,596 (+)NCBINCBI36hg18NCBI36
Build 34819,215,486 - 19,297,594NCBI
Celera818,134,620 - 18,217,068 (+)NCBI
Cytogenetic Map8p21.3NCBI
HuRef817,711,708 - 17,794,051 (+)NCBIHuRef
CHM1_1819,372,569 - 19,455,187 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on SH2D4A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317502
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.