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Gene: PHC3 (polyhomeotic homolog 3) Homo sapiens
Symbol: PHC3
Name: polyhomeotic homolog 3
Description: Predicted to have DNA binding activity and zinc ion binding activity. Predicted to be involved in negative regulation of G0 to G1 transition. Localizes to the PRC1 complex and nucleoplasm; PARTICIPATES IN histone modification pathway; INTERACTS WITH 17beta-estradiol; aflatoxin B1; aflatoxin B2.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp313K1221; early development regulator 3; early development regulatory protein 3; EDR3; FLJ12729; FLJ12967; homolog of polyhomeotic 3; HPH3; MGC88144; polyhomeotic like 3; polyhomeotic like 3 (drosophila); polyhomeotic-like protein 3
Mus musculus (house mouse) : Phc3 (polyhomeotic 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Phc3 (polyhomeotic homolog 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Phc3 (polyhomeotic homolog 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PHC3 (polyhomeotic homolog 3)
Canis lupus familiaris (dog) : PHC3 (polyhomeotic homolog 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Phc3 (polyhomeotic homolog 3)
Sus scrofa (pig) : PHC3 (polyhomeotic homolog 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh383170,087,580 - 170,181,752 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373169,805,368 - 169,899,537 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363171,288,062 - 171,382,231 (-)NCBINCBI36hg18NCBI36
Build 343171,297,359 - 171,382,218NCBI
Celera3168,204,684 - 168,298,819 (-)NCBI
Cytogenetic Map3q26.2NCBI
HuRef3167,175,971 - 167,270,090 (-)NCBIHuRef
CHM1_13169,768,808 - 169,862,971 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PHC3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317513
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.