Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Lrrk1 (leucine-rich repeat kinase 1) Mus musculus
Analyze
Symbol: Lrrk1
Name: leucine-rich repeat kinase 1
Description: Predicted to have identical protein binding activity. Involved in several processes, including bone resorption; osteoclast development; and regulation of peptidyl-tyrosine phosphorylation. Predicted to localize to the cytosol and mitochondrion. Used to study osteopetrosis. Is expressed in several structures, including gut; immune system; liver; lung; and musculature. Orthologous to human LRRK1 (leucine rich repeat kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW319595; C230002E15Rik; D130026O16Rik; leucine-rich repeat serine/threonine-protein kinase 1; MGC28646; mKIAA1790
Orthologs:
Homo sapiens (human) : LRRK1 (leucine rich repeat kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lrrk1 (leucine-rich repeat kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrrk1 (leucine rich repeat kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LRRK1 (leucine rich repeat kinase 1)
Canis lupus familiaris (dog) : LRRK1 (leucine rich repeat kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrrk1 (leucine rich repeat kinase 1)
Sus scrofa (pig) : LRRK1 (leucine rich repeat kinase 1)
Chlorocebus sabaeus (green monkey) : LRRK1 (leucine rich repeat kinase 1)
Heterocephalus glaber (naked mole-rat) : Lrrk1 (leucine rich repeat kinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl766,226,912 - 66,388,350 (-)Ensembl
GRCm38766,258,745 - 66,388,341 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37773,403,631 - 73,533,227 (-)NCBIGRCm37mm9NCBIm37
MGSCv36766,137,695 - 66,267,291 (-)NCBImm8
MGSCv36755,670,181 - 55,799,947 (-)NCBImm8
Celera763,712,568 - 63,843,036 (-)NCBICelera
Celera759,723,311 - 59,724,078 (-)NCBICelera
Cytogenetic Map7 CNCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Lrrk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317517
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.