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Gene: Lrrk1 (leucine-rich repeat kinase 1) Mus musculus
Symbol: Lrrk1
Name: leucine-rich repeat kinase 1
Description: Predicted to have identical protein binding activity. Involved in several processes, including bone resorption; osteoclast development; and regulation of peptidyl-tyrosine phosphorylation. Predicted to localize to the cytosol and mitochondrion. Used to study osteopetrosis. Is expressed in several structures, including gut; immune system; liver; lung; and musculature. Orthologous to human LRRK1 (leucine rich repeat kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW319595; C230002E15Rik; D130026O16Rik; leucine-rich repeat serine/threonine-protein kinase 1; MGC28646; mKIAA1790
Homo sapiens (human) : LRRK1 (leucine rich repeat kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Lrrk1 (leucine-rich repeat kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lrrk1 (leucine rich repeat kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LRRK1 (leucine rich repeat kinase 1)
Canis lupus familiaris (dog) : LRRK1 (leucine rich repeat kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lrrk1 (leucine rich repeat kinase 1)
Sus scrofa (pig) : LRRK1 (leucine rich repeat kinase 1)
Chlorocebus sabaeus (green monkey) : LRRK1 (leucine rich repeat kinase 1)
Heterocephalus glaber (naked mole-rat) : Lrrk1 (leucine rich repeat kinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl766,226,912 - 66,388,350 (-)Ensembl
GRCm38766,258,745 - 66,388,341 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37773,403,631 - 73,533,227 (-)NCBIGRCm37mm9NCBIm37
MGSCv36766,137,695 - 66,267,291 (-)NCBImm8
MGSCv36755,670,181 - 55,799,947 (-)NCBImm8
Celera763,712,568 - 63,843,036 (-)NCBICelera
Celera759,723,311 - 59,724,078 (-)NCBICelera
Cytogenetic Map7 CNCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Lrrk1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317517
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-12-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.