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Gene: Rnf8 (ring finger protein 8) Mus musculus
Symbol: Rnf8
Name: ring finger protein 8
Description: Exhibits histone binding activity and ubiquitin protein ligase activity. Involved in DNA metabolic process and chromatin organization. Localizes to the chromosome, telomeric region; cytoplasm; and nucleus. Is expressed in central nervous system; genitourinary system; nasal cavity epithelium; and thymus primordium. Orthologous to human RNF8 (ring finger protein 8); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3830404E21Rik; ActA binding protein 2; actA-interacting protein 37; AIP37; E3 ubiquitin-protein ligase RNF8; laXp180; RING-type E3 ubiquitin transferase RNF8
Homo sapiens (human) : RNF8 (ring finger protein 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rnf8 (ring finger protein 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf8 (ring finger protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF8 (ring finger protein 8)
Canis lupus familiaris (dog) : RNF8 (ring finger protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf8 (ring finger protein 8)
Sus scrofa (pig) : RNF8 (ring finger protein 8)
Chlorocebus sabaeus (African green monkey) : RNF8 (ring finger protein 8)
Heterocephalus glaber (naked mole-rat) : Rnf8 (ring finger protein 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1729,614,790 - 29,644,991 (+)Ensembl
GRCm381729,614,789 - 29,641,664 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371729,751,776 - 29,778,604 (+)NCBIGRCm37mm9NCBIm37
MGSCv361729,341,843 - 29,368,671 (+)NCBImm8
MGSCv361728,828,664 - 28,855,463 (+)NCBImm8
Celera1730,155,441 - 30,176,366 (+)NCBICelera
Cytogenetic Map17 A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Rnf8
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317572
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.