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Gene: Rnf8 (ring finger protein 8) Mus musculus
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Symbol: Rnf8
Name: ring finger protein 8
Description: Exhibits histone binding activity and ubiquitin protein ligase activity. Involved in DNA metabolic process and chromatin organization. Localizes to the chromosome, telomeric region; cytoplasm; and nucleus. Is expressed in central nervous system; genitourinary system; nasal cavity epithelium; and thymus primordium. Orthologous to human RNF8 (ring finger protein 8); PARTICIPATES IN ataxia telangiectasia-mutated (ATM) signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3830404E21Rik; ActA binding protein 2; actA-interacting protein 37; AIP37; E3 ubiquitin-protein ligase RNF8; laXp180; RING-type E3 ubiquitin transferase RNF8
Orthologs:
Homo sapiens (human) : RNF8 (ring finger protein 8)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Rnf8 (ring finger protein 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rnf8 (ring finger protein 8)
Pan paniscus (bonobo/pygmy chimpanzee) : RNF8 (ring finger protein 8)
Canis lupus familiaris (dog) : RNF8 (ring finger protein 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rnf8 (ring finger protein 8)
Sus scrofa (pig) : RNF8 (ring finger protein 8)
Chlorocebus sabaeus (African green monkey) : RNF8 (ring finger protein 8)
Heterocephalus glaber (naked mole-rat) : Rnf8 (ring finger protein 8)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1729,614,790 - 29,644,991 (+)Ensembl
GRCm381729,614,789 - 29,641,664 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371729,751,776 - 29,778,604 (+)NCBIGRCm37mm9NCBIm37
MGSCv361729,341,843 - 29,368,671 (+)NCBImm8
MGSCv361728,828,664 - 28,855,463 (+)NCBImm8
Celera1730,155,441 - 30,176,366 (+)NCBICelera
Cytogenetic Map17 A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Rnf8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317572
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.