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Gene: POLR3E (RNA polymerase III subunit E) Homo sapiens
Symbol: POLR3E
Name: RNA polymerase III subunit E
Description: Predicted to contribute to RNA polymerase III activity. Predicted to be involved in positive regulation of type I interferon production. Localizes to the RNA polymerase III complex and nucleoplasm; PARTICIPATES IN purine metabolic pathway; pyrimidine metabolic pathway; RNA polymerase III transcription pathway; INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one; 2,3,7,8-tetrachlorodibenzodioxine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DNA-directed RNA polymerase III 80 kDa polypeptide; DNA-directed RNA polymerase III subunit RPC5; polymerase (RNA) III (DNA directed) polypeptide E (80kD); polymerase (RNA) III subunit E; RNA polymerase III 80 kDa subunit RPC5; RNA polymerase III subunit C5; RPC5; SIN
Mus musculus (house mouse) : Polr3e (polymerase (RNA) III (DNA directed) polypeptide E)  MGI  Alliance
Rattus norvegicus (Norway rat) : Polr3e (RNA polymerase III subunit E)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polr3e (RNA polymerase III subunit E)
Pan paniscus (bonobo/pygmy chimpanzee) : POLR3E (RNA polymerase III subunit E)
Canis lupus familiaris (dog) : POLR3E (RNA polymerase III subunit E)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polr3e (RNA polymerase III subunit E)
Sus scrofa (pig) : POLR3E (RNA polymerase III subunit E)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381622,297,375 - 22,335,103 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371622,308,696 - 22,346,424 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361622,216,242 - 22,252,847 (+)NCBINCBI36hg18NCBI36
Build 341622,216,241 - 22,252,842NCBI
Celera1621,088,628 - 21,125,238 (+)NCBI
Cytogenetic Map16p12.2NCBI
HuRef1620,553,291 - 20,591,117 (+)NCBIHuRef
CHM1_11622,044,894 - 22,082,622 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on POLR3E
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317654
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.