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Gene: CACUL1 (CDK2 associated cullin domain 1) Homo sapiens
Symbol: CACUL1
Name: CDK2 associated cullin domain 1
Description: Exhibits protein kinase binding activity. Involved in G1/S transition of mitotic cell cycle; positive regulation of cell population proliferation; and positive regulation of protein kinase activity; INTERACTS WITH aflatoxin B1; benzo[e]pyrene; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C10orf46; CAC1; Cdk-Associated Cullin1; CDK2-associated and cullin domain-containing protein 1; CDK2-associated, cullin domain 1; chromosome 10 open reading frame 46; cullin; FLJ40409; MGC33215; uncharacterized protein C10orf46
Mus musculus (house mouse) : Cacul1 (CDK2 associated, cullin domain 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cacul1 (CDK2-associated, cullin domain 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cacul1 (CDK2 associated cullin domain 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CACUL1 (CDK2 associated cullin domain 1)
Canis lupus familiaris (dog) : CACUL1 (CDK2 associated cullin domain 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cacul1 (CDK2 associated cullin domain 1)
Sus scrofa (pig) : CACUL1 (CDK2 associated cullin domain 1)
Chlorocebus sabaeus (African green monkey) : CACUL1 (CDK2 associated cullin domain 1)
Heterocephalus glaber (naked mole-rat) : Cacul1 (CDK2 associated cullin domain 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl10118,674,167 - 118,755,249 (-)EnsemblGRCh38hg38GRCh38
GRCh3810118,676,411 - 118,754,970 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710120,433,679 - 120,514,758 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610120,430,484 - 120,504,748 (-)NCBINCBI36hg18NCBI36
Build 3410120,432,909 - 120,504,748NCBI
Celera10114,171,140 - 114,245,410 (-)NCBI
Cytogenetic Map10q26.11NCBI
HuRef10114,069,583 - 114,143,787 (-)NCBIHuRef
CHM1_110120,724,839 - 120,799,135 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CACUL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 1317719
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.